Men's Health
Men's Health After 40: Labs and Screenings Worth Discussing
October 8, 2026 Vitality Medicine RX Editorial Team
For men after 40, the core preventive screenings are blood pressure, cholesterol, blood sugar, colorectal cancer screening starting at 45, and an individualized discussion about PSA testing. Beyond those, hormone and metabolic labs can add useful context when symptoms like fatigue, low libido or weight gain are present. Vitality Medicine RX offers nurse practitioner-led telehealth care in states where Dr. Miklos Major II, Sc.D., DNP, NP-BC, FAAMFM holds an active license.
Screenings with clear recommendations
- Blood pressure, checked at least every one to two years
- Cholesterol (lipid panel), recommended for men starting at age 35
- Blood sugar or A1C screening for adults 35 to 70 with overweight or obesity, and every three years from age 45 for average-risk adults
- Colorectal cancer screening starting at age 45
PSA testing is an individual decision
The U.S. Preventive Services Task Force recommends that men ages 55 to 69 discuss the potential benefits and harms of PSA-based prostate cancer screening with a clinician before deciding, and it recommends against routine PSA screening for men 70 and older. This is a conversation, not a checkbox.
Hormone and metabolic labs that add context
When symptoms such as fatigue, low libido, poor sleep or weight gain are present, additional labs can help: total and free testosterone, estradiol, thyroid markers, A1C, fasting glucose and insulin, lipids and vitamin D. Testing is chosen based on your history and goals, not ordered by the handful.
What this means for you
Preventive screening is about catching problems early, and labs are interpreted in context. Your regular clinician remains central to routine screening, and a functional medicine evaluation can add an additional layer of understanding.
When to talk to a clinician
If you are due for labs or want a clearer picture of your health after 40, book a discovery call. We will confirm we can see you in your state and outline which evaluations may be appropriate.
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Talk to a Clinician
This article is educational and does not replace individualized medical advice. If you have questions about your own health, book a discovery call with Vitality Medicine RX. Your care is led by Dr. Miklos Major II, Sc.D., DNP, NP-BC, FAAMFM, a Doctor of Nursing Practice (DNP) and Doctor of Science (Sc.D.), board-certified nurse practitioner (NP-BC). Care is available in states where he holds an active license.
Book a Discovery CallQuestions About This Topic
What blood tests should a man over 40 get?
At minimum, cholesterol and blood sugar screening. Hormone, thyroid and metabolic labs are added based on symptoms and history.
When should men start colorectal cancer screening?
The U.S. Preventive Services Task Force recommends starting colorectal cancer screening at age 45.
Should every man over 40 get a PSA test?
No. For men 55 to 69 it is an individual decision after discussing benefits and harms with a clinician, and routine screening is not recommended for men 70 and older.
How do I get labs done?
Book a discovery call. Labs are ordered after an intake and completed near you or with a home kit where available, depending on your state.
Last updated 2026-10-08.